In a televised speech, he slammed the story of Adam and Eve’s fall from grace in the Bible and the logic behind the Christian concept of original sin.
Duterte is well known known for his outrageous statements and unfiltered attacks on his rivals.
While the church and many citizens condemned his remarks, his office said he was expressing personal beliefs.
The President has in the past also criticised the Pope in crude language and has racked up a string of other statements widely deemed as highly offensive, cruel or misogynist.
His latest comments came at a speech in Davao, the city he governed as a major before running as president.
Asking “Who is this stupid God?”, Duterte criticised the Biblical story of creation and Adam and Eve being thrown out of the Garden of Eden after they ate the “forbidden fruit”.
“You created something perfect and then you think of an event that would tempt and destroy the quality of your work,” he said.
The president also slammed the concept of original sin – whereby all humans are tainted by Adam and Eve’s wrongdoing – saying: “You weren’t born yet, but now you have original sin.”
“What kind of religion is that? I can’t accept it.”
Vote for Okay Nigeria (Okay.ng) as BEST ONLINE MEDIA WEBSITE at 2019 .NG awards HERE