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Reading: Nigeria approves 80% effective R21/Matrix malaria vaccine developed by Oxford scientists
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Nigeria approves 80% effective R21/Matrix malaria vaccine developed by Oxford scientists

Muhammad A. Aliyu
By Muhammad A. Aliyu
Published: April 17, 2023
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Nigeria has granted provisional approval for the R21/Matrix malaria vaccine developed by scientists at Oxford University.

The vaccine is said to be 80% effective and is manufactured by the Serum Institute of India Pvt Ltd.

The announcement was made by Mojisola Adeyeye, director-general of the National Agency for Food and Drug Administration and Control (NAFDAC), at a press briefing on Monday.

“The National Agency for Food and Drug Administration and Control (NAFDAC) in exercising its mandate as stipulated by its enabling law, NAFDAC Act CapN1, LFN 2004 is granting registration approval for R21 malaria vaccine,” Adeyeye said.

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According to her, the vaccine is indicated for the prevention of clinical malaria in children from five months to 36 months of age and should be stored at a temperature of 2-8°C.

Adeyeye further revealed that NAFDAC received the dossier of the R21 and subjected it to independent review by experts from Nigeria’s tertiary institutions and the agency’s in-house vaccine review committee.

She also said that a joint review was then conducted after the team assessed the vaccine as “adequate” and the in-house committee also assessed it as “satisfactory.”

“Overall, the R21 malaria vaccine dossier complied substantially with best international standards with which the dossier was benched-marked as mentioned above. The joint review committee concluded that the data on the R21 malaria vaccine were robust and met criteria for efficacy, safety, and quality,” she said.

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“It was also adjudged that the vaccine’s known and potential benefits outweigh its known and potential risks, thereby supporting the manufacturer’s recommended use.

“A provisional approval of the R21 malaria vaccine was recommended and this shall be done in line with the WHO’s malaria vaccine implementation guideline.

“While granting the approval, the agency has also communicated the need for expansion of the clinical trial conducted to include a phase 4 clinical trial/pharmacovigilance study to be carried out in Nigeria.

“The brief on the approval of the R21 Malaria vaccine has been communicated to the minister of health and national primary health care development agency for appropriate actions toward immunisation in the respective population.”

The approval comes just days after Ghana became the first country to approve the vaccine.

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TAGGED:Malaria VaccineNigeria
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ByMuhammad A. Aliyu
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Muhammad Ameer Aliyu, is a prolific journalist who joined Okay Nigeria in 2015 with the aim staying committed to bringing more positive growth to the digital news platform. He is the Senior Editor at Okay Nigeria.
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